Expanding the Medicinal Chemist Toolbox: Comparing Seven C(sp(2))–C(sp(3)) Cross-Coupling Methods by Library Synthesis

[Image: see text] Despite recent advances in the field of C(sp(2))–C(sp(3)) cross-couplings and the accompanying increase in publications, it can be hard to determine which method is appropriate for a given reaction when using the highly functionalized intermediates prevalent in medicinal chemistry....

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Detalles Bibliográficos
Autores principales: Dombrowski, Amanda W., Gesmundo, Nathan J., Aguirre, Ana L., Sarris, Katerina A., Young, Jonathon M., Bogdan, Andrew R., Martin, M. Cynthia, Gedeon, Shasline, Wang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153271/
https://www.ncbi.nlm.nih.gov/pubmed/32292569
http://dx.doi.org/10.1021/acsmedchemlett.0c00093

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