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Draft genome sequence data of Streptomyces sp. SS1-1, an endophytic strain showing cytotoxicity against the human lung cancer A549 cell line
We report in this article the cytotoxicity of Streptomyces sp. SS1-1 against the human lung cancer A549 cell line, its draft genome sequence and a total of 20 predicted secondary metabolite biosynthetic gene clusters. Streptomyces sp. SS1-1 was an endophytic bacterial strain isolated from the plant...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153288/ https://www.ncbi.nlm.nih.gov/pubmed/32300629 http://dx.doi.org/10.1016/j.dib.2020.105497 |
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author | Nguyen, Quan Dang Truong, Phung Minh Vo, Thao Nguyen Thanh Chu, Truc Dao Xuan Nguyen, Chuong Hoang |
author_facet | Nguyen, Quan Dang Truong, Phung Minh Vo, Thao Nguyen Thanh Chu, Truc Dao Xuan Nguyen, Chuong Hoang |
author_sort | Nguyen, Quan Dang |
collection | PubMed |
description | We report in this article the cytotoxicity of Streptomyces sp. SS1-1 against the human lung cancer A549 cell line, its draft genome sequence and a total of 20 predicted secondary metabolite biosynthetic gene clusters. Streptomyces sp. SS1-1 was an endophytic bacterial strain isolated from the plant Catharanthus roseus in Ho Chi Minh City, Vietnam. When cultured in the PY medium, this strain shows a cytotoxic effect on the A549 cell line. The draft genome of Streptomyces sp. SS1-1 has four contigs of total 7,815,656 bp and the GC content of this genome is 72.2%. AntiSMASH analysis reveals 20 putative biosynthetic gene clusters for the largest contig. The genome sequencing of Streptomyces sp. SS1-1 is essential for the molecular identification of gene cluster(s) responsible for secondary metabolite(s) with cytotoxic activity. |
format | Online Article Text |
id | pubmed-7153288 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-71532882020-04-16 Draft genome sequence data of Streptomyces sp. SS1-1, an endophytic strain showing cytotoxicity against the human lung cancer A549 cell line Nguyen, Quan Dang Truong, Phung Minh Vo, Thao Nguyen Thanh Chu, Truc Dao Xuan Nguyen, Chuong Hoang Data Brief Genetics, Genomics and Molecular Biology We report in this article the cytotoxicity of Streptomyces sp. SS1-1 against the human lung cancer A549 cell line, its draft genome sequence and a total of 20 predicted secondary metabolite biosynthetic gene clusters. Streptomyces sp. SS1-1 was an endophytic bacterial strain isolated from the plant Catharanthus roseus in Ho Chi Minh City, Vietnam. When cultured in the PY medium, this strain shows a cytotoxic effect on the A549 cell line. The draft genome of Streptomyces sp. SS1-1 has four contigs of total 7,815,656 bp and the GC content of this genome is 72.2%. AntiSMASH analysis reveals 20 putative biosynthetic gene clusters for the largest contig. The genome sequencing of Streptomyces sp. SS1-1 is essential for the molecular identification of gene cluster(s) responsible for secondary metabolite(s) with cytotoxic activity. Elsevier 2020-04-08 /pmc/articles/PMC7153288/ /pubmed/32300629 http://dx.doi.org/10.1016/j.dib.2020.105497 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Genetics, Genomics and Molecular Biology Nguyen, Quan Dang Truong, Phung Minh Vo, Thao Nguyen Thanh Chu, Truc Dao Xuan Nguyen, Chuong Hoang Draft genome sequence data of Streptomyces sp. SS1-1, an endophytic strain showing cytotoxicity against the human lung cancer A549 cell line |
title | Draft genome sequence data of Streptomyces sp. SS1-1, an endophytic strain showing cytotoxicity against the human lung cancer A549 cell line |
title_full | Draft genome sequence data of Streptomyces sp. SS1-1, an endophytic strain showing cytotoxicity against the human lung cancer A549 cell line |
title_fullStr | Draft genome sequence data of Streptomyces sp. SS1-1, an endophytic strain showing cytotoxicity against the human lung cancer A549 cell line |
title_full_unstemmed | Draft genome sequence data of Streptomyces sp. SS1-1, an endophytic strain showing cytotoxicity against the human lung cancer A549 cell line |
title_short | Draft genome sequence data of Streptomyces sp. SS1-1, an endophytic strain showing cytotoxicity against the human lung cancer A549 cell line |
title_sort | draft genome sequence data of streptomyces sp. ss1-1, an endophytic strain showing cytotoxicity against the human lung cancer a549 cell line |
topic | Genetics, Genomics and Molecular Biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153288/ https://www.ncbi.nlm.nih.gov/pubmed/32300629 http://dx.doi.org/10.1016/j.dib.2020.105497 |
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