Eliminating effects of particle adsorption to the air/water interface in single-particle cryo-electron microscopy: Bacterial RNA polymerase and CHAPSO

Preferred particle orientation presents a major challenge for many single particle cryo-electron microscopy (cryo-EM) samples. Orientation bias limits the angular information used to generate three-dimensional maps and thus affects the reliability and interpretability of the structural models. The p...

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Detalles Bibliográficos
Autores principales: Chen, James, Noble, Alex J., Kang, Jin Young, Darst, Seth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153306/
https://www.ncbi.nlm.nih.gov/pubmed/32285040
http://dx.doi.org/10.1016/j.yjsbx.2019.100005

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