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The Use of Electrospun Organic and Carbon Nanofibers in Bone Regeneration
There has been an increasing amount of research on regenerative medicine for the treatment of bone defects. Scaffolds are needed for the formation of new bone, and various scaffolding materials have been evaluated for bone regeneration. Materials with pores that allow cells to differentiate into ost...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153397/ https://www.ncbi.nlm.nih.gov/pubmed/32244931 http://dx.doi.org/10.3390/nano10030562 |
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author | Aoki, Kaoru Haniu, Hisao Kim, Yoong Ahm Saito, Naoto |
author_facet | Aoki, Kaoru Haniu, Hisao Kim, Yoong Ahm Saito, Naoto |
author_sort | Aoki, Kaoru |
collection | PubMed |
description | There has been an increasing amount of research on regenerative medicine for the treatment of bone defects. Scaffolds are needed for the formation of new bone, and various scaffolding materials have been evaluated for bone regeneration. Materials with pores that allow cells to differentiate into osteocytes are preferred in scaffolds for bone regeneration, and porous materials and fibers are well suited for this application. Electrospinning is an effective method for producing a nanosized fiber by applying a high voltage to the needle tip containing a polymer solution. The use of electrospun nanofibers is being studied in the medical field, and its use as a scaffold for bone regeneration therapy has become a topic of growing interest. In this review, we will introduce the potential use of electrospun nanofiber as a scaffold for bone regenerative medicine with a focus on carbon nanofibers produced by the electrospinning method. |
format | Online Article Text |
id | pubmed-7153397 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-71533972020-04-20 The Use of Electrospun Organic and Carbon Nanofibers in Bone Regeneration Aoki, Kaoru Haniu, Hisao Kim, Yoong Ahm Saito, Naoto Nanomaterials (Basel) Review There has been an increasing amount of research on regenerative medicine for the treatment of bone defects. Scaffolds are needed for the formation of new bone, and various scaffolding materials have been evaluated for bone regeneration. Materials with pores that allow cells to differentiate into osteocytes are preferred in scaffolds for bone regeneration, and porous materials and fibers are well suited for this application. Electrospinning is an effective method for producing a nanosized fiber by applying a high voltage to the needle tip containing a polymer solution. The use of electrospun nanofibers is being studied in the medical field, and its use as a scaffold for bone regeneration therapy has become a topic of growing interest. In this review, we will introduce the potential use of electrospun nanofiber as a scaffold for bone regenerative medicine with a focus on carbon nanofibers produced by the electrospinning method. MDPI 2020-03-20 /pmc/articles/PMC7153397/ /pubmed/32244931 http://dx.doi.org/10.3390/nano10030562 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Aoki, Kaoru Haniu, Hisao Kim, Yoong Ahm Saito, Naoto The Use of Electrospun Organic and Carbon Nanofibers in Bone Regeneration |
title | The Use of Electrospun Organic and Carbon Nanofibers in Bone Regeneration |
title_full | The Use of Electrospun Organic and Carbon Nanofibers in Bone Regeneration |
title_fullStr | The Use of Electrospun Organic and Carbon Nanofibers in Bone Regeneration |
title_full_unstemmed | The Use of Electrospun Organic and Carbon Nanofibers in Bone Regeneration |
title_short | The Use of Electrospun Organic and Carbon Nanofibers in Bone Regeneration |
title_sort | use of electrospun organic and carbon nanofibers in bone regeneration |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153397/ https://www.ncbi.nlm.nih.gov/pubmed/32244931 http://dx.doi.org/10.3390/nano10030562 |
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