A Pharmacogenetically Guided Acenocoumarol Dosing Algorithm for Chilean Patients: A Discovery Cohort Study

BACKGROUND: Vitamin K antagonists (VKA) are used as prophylaxis for thromboembolic events in patients with cardiovascular diseases. The most common VKA are warfarin and acenocoumarol. These drugs have a narrow therapeutic margin and high inter-individual response variability due to clinical and phar...

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Detalles Bibliográficos
Autores principales: Roco, Angela, Nieto, Elena, Suárez, Marcelo, Rojo, Mario, Bertoglia, Maria Paz, Verón, Gabriel, Tamayo, Francisca, Arredondo, Annabella, Cruz, Daniela, Muñoz, Jessica, Bravo, Gabriela, Salas, Patricio, Mejías, Fanny, Godoy, Gerald, Véliz, Paulo, Quiñones, Luis Abel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153463/
https://www.ncbi.nlm.nih.gov/pubmed/32327994
http://dx.doi.org/10.3389/fphar.2020.00325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153463/
https://www.ncbi.nlm.nih.gov/pubmed/32327994
http://dx.doi.org/10.3389/fphar.2020.00325

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