Target Virus or Target Ourselves for COVID-19 Drugs Discovery?―Lessons learned from anti-influenza virus therapies

The COVID-19 pandemic, after it was reported in December 2019, is a highly contagious and now spreading to over 190 countries, causing a severe public health burden. Currently, there is no vaccine or specific drug to treat COVID-19, which is caused by a novel coronavirus, SARS-2-CoV. For this emerge...

Descripción completa

Detalles Bibliográficos
Autores principales: Liao, Jiayu, Way, George, Madahar, Vipul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153514/
https://www.ncbi.nlm.nih.gov/pubmed/32292909
http://dx.doi.org/10.1016/j.medidd.2020.100037
_version_ 1783521667200319488
author Liao, Jiayu
Way, George
Madahar, Vipul
author_facet Liao, Jiayu
Way, George
Madahar, Vipul
author_sort Liao, Jiayu
collection PubMed
description The COVID-19 pandemic, after it was reported in December 2019, is a highly contagious and now spreading to over 190 countries, causing a severe public health burden. Currently, there is no vaccine or specific drug to treat COVID-19, which is caused by a novel coronavirus, SARS-2-CoV. For this emergency, the FDA has approved Remdesivir and Hydroxychloroquine for treatment of COVID-19 as Emergency Use Authorization. However, even after this pandemic, COVID-19 may still have a chance to come back. Therefore, we need to come out with new strategies for drug discovery for combating COVID-19 in the future.
format Online
Article
Text
id pubmed-7153514
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher The Authors. Published by Elsevier B.V.
record_format MEDLINE/PubMed
spelling pubmed-71535142020-04-14 Target Virus or Target Ourselves for COVID-19 Drugs Discovery?―Lessons learned from anti-influenza virus therapies Liao, Jiayu Way, George Madahar, Vipul Med Drug Discov Article The COVID-19 pandemic, after it was reported in December 2019, is a highly contagious and now spreading to over 190 countries, causing a severe public health burden. Currently, there is no vaccine or specific drug to treat COVID-19, which is caused by a novel coronavirus, SARS-2-CoV. For this emergency, the FDA has approved Remdesivir and Hydroxychloroquine for treatment of COVID-19 as Emergency Use Authorization. However, even after this pandemic, COVID-19 may still have a chance to come back. Therefore, we need to come out with new strategies for drug discovery for combating COVID-19 in the future. The Authors. Published by Elsevier B.V. 2020-03 2020-04-13 /pmc/articles/PMC7153514/ /pubmed/32292909 http://dx.doi.org/10.1016/j.medidd.2020.100037 Text en © 2020 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Liao, Jiayu
Way, George
Madahar, Vipul
Target Virus or Target Ourselves for COVID-19 Drugs Discovery?―Lessons learned from anti-influenza virus therapies
title Target Virus or Target Ourselves for COVID-19 Drugs Discovery?―Lessons learned from anti-influenza virus therapies
title_full Target Virus or Target Ourselves for COVID-19 Drugs Discovery?―Lessons learned from anti-influenza virus therapies
title_fullStr Target Virus or Target Ourselves for COVID-19 Drugs Discovery?―Lessons learned from anti-influenza virus therapies
title_full_unstemmed Target Virus or Target Ourselves for COVID-19 Drugs Discovery?―Lessons learned from anti-influenza virus therapies
title_short Target Virus or Target Ourselves for COVID-19 Drugs Discovery?―Lessons learned from anti-influenza virus therapies
title_sort target virus or target ourselves for covid-19 drugs discovery?―lessons learned from anti-influenza virus therapies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153514/
https://www.ncbi.nlm.nih.gov/pubmed/32292909
http://dx.doi.org/10.1016/j.medidd.2020.100037
work_keys_str_mv AT liaojiayu targetvirusortargetourselvesforcovid19drugsdiscoverylessonslearnedfromantiinfluenzavirustherapies
AT waygeorge targetvirusortargetourselvesforcovid19drugsdiscoverylessonslearnedfromantiinfluenzavirustherapies
AT madaharvipul targetvirusortargetourselvesforcovid19drugsdiscoverylessonslearnedfromantiinfluenzavirustherapies

Ejemplares similares