Cargando…

Antibody-mediated neutralization of ACBP/DBI has anorexigenic and lipolytic effects

We recently identified acyl coenzyme A-binding protein (ACBP)/diazepam binding inhibitor (DBI) as a novel ‘hunger factor’: a protein that is upregulated in human or murine obesity and that, if administered to mice, causes hyperphagy, adipogenesis and obesity. Conversely, neutralization of ACBP/DBI b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sica, Valentina, Martins, Isabelle, Motiño, Omar, Bravo-San Pedro, José M., Kroemer, Guido
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153538/ https://www.ncbi.nlm.nih.gov/pubmed/32157940 http://dx.doi.org/10.1080/21623945.2020.1736734

Ejemplares similares

Elevated plasma levels of the appetite-stimulator ACBP/DBI in fasting and obese subjects
por: Li, Sijing, et al.
Publicado: (2021)

Immunization of mice with the self-peptide ACBP coupled to keyhole limpet hemocyanin
por: Montégut, Léa, et al.
Publicado: (2022)

ACBP/DBI protein neutralization confers autophagy-dependent organ protection through inhibition of cell loss, inflammation, and fibrosis
por: Motiño, Omar, et al.
Publicado: (2022)

DBI/ACBP is a targetable autophagy checkpoint involved in aging and cardiovascular disease
por: Montégut, Léa, et al.
Publicado: (2022)

Effects of acyl-coenzyme A binding protein (ACBP)/diazepam-binding inhibitor (DBI) on body mass index
por: Joseph, Adrien, et al.
Publicado: (2021)

Metabolic and psychiatric effects of acyl coenzyme A binding protein (ACBP)/diazepam binding inhibitor (DBI)
por: Joseph, Adrien, et al.
Publicado: (2020)

Acyl-CoA-binding protein (ACBP): the elusive ‘hunger factor' linking autophagy to food intake
por: Pedro, José Manuel Bravo-San, et al.
Publicado: (2019)

Acyl coenzyme A binding protein (ACBP): An aging‐ and disease‐relevant “autophagy checkpoint”
por: Montégut, Léa, et al.
Publicado: (2023)

ACBP is an appetite stimulator across phylogenetic barriers
por: Madeo, Frank, et al.
Publicado: (2020)

Acyl-CoA-binding protein (ACBP): a phylogenetically conserved appetite stimulator
por: Charmpilas, Nikolaos, et al.
Publicado: (2020)

High plasma concentrations of acyl‐coenzyme A binding protein (ACBP) predispose to cardiovascular disease: Evidence for a phylogenetically conserved proaging function of ACBP
por: Montégut, Léa, et al.
Publicado: (2022)

Programming the Perl DBI
por: Descartes, Alligator, et al.
Publicado: (2000)

Arabidopsis cytosolic acyl-CoA-binding proteins ACBP4, ACBP5 and ACBP6 have overlapping but distinct roles in seed development
por: Hsiao, An-Shan, et al.
Publicado: (2014)

Arabidopsis cytosolic acyl-CoA-binding proteins ACBP4, ACBP5 and ACBP6 have overlapping but distinct roles in seed development
por: Hsiao, A. S., et al.
Publicado: (2015)

Pseudodiabetes—not a contraindication for metabolic interventions
por: Bravo-San Pedro, José Manuel, et al.
Publicado: (2019)

The elusive “hunger protein”: an appetite-stimulatory factor that is overabundant in human obesity
por: Bravo-San Pedro, José Manuel, et al.
Publicado: (2019)

Brane Bremsstrahlung in DBI Inflation
por: Brax, Philippe, et al.
Publicado: (2009)

Protein regulator of cytokinesis 1: a potential oncogenic driver
por: Li, Sijing, et al.
Publicado: (2023)

Multifield DBI Inflation and Non-Gaussianities
por: Huang, Min-xin, et al.
Publicado: (2007)

Distinct Plasma Concentrations of Acyl-CoA-Binding Protein (ACBP) in HIV Progressors and Elite Controllers
por: Isnard, Stéphane, et al.
Publicado: (2022)

Lipocalin-2 is an anorexigenic signal in primates
por: Petropoulou, Peristera-Ioanna, et al.
Publicado: (2020)

Dirac Born Infeld (DBI) Cosmic Strings
por: Babichev, Eugeny, et al.
Publicado: (2008)

Subcellular Localization of Rice Acyl-CoA-Binding Proteins ACBP4 and ACBP5 Supports Their Non-redundant Roles in Lipid Metabolism
por: Liao, Pan, et al.
Publicado: (2020)

Serum DBI and biomarkers of neuroinflammation in Alzheimer’s disease and delirium
por: Conti, Elisa, et al.
Publicado: (2020)

Interactions of Gastrointestinal Peptides: Ghrelin and Its Anorexigenic Antagonists
por: Wisser, Anna-Sophia, et al.
Publicado: (2010)

Xenin is a novel anorexigen in goldfish (Carassius auratus)
por: Kerbel, Brent, et al.
Publicado: (2018)

Recent progress on action and regulation of anorexigenic adipokine leptin
por: Nakagawa, Tadashi, et al.
Publicado: (2023)

BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy
por: Pedro, Jose Manuel Bravo-San, et al.
Publicado: (2015)

Primordial perturbations and non-Gaussianities in DBI and general multi-field inflation
por: Langlois, David, et al.
Publicado: (2008)

Spatial multi-omics sequencing for fixed tissue via DBiT-seq
por: Su, Graham, et al.
Publicado: (2021)

DbyDeep: Exploration of MS-Detectable Peptides via Deep Learning
por: Son, Juho, et al.
Publicado: (2023)

The Food-Contaminant Deoxynivalenol Modifies Eating by Targeting Anorexigenic Neurocircuitry
por: Girardet, Clémence, et al.
Publicado: (2011)

(−)-Epigallocatechin-3-gallate induces secretion of anorexigenic gut hormones
por: Song, Won-Young, et al.
Publicado: (2015)

Limiting glucocorticoid secretion increases the anorexigenic property of Exendin-4
por: Lee, Shin J., et al.
Publicado: (2016)

Estradiol Drives the Anorexigenic Activity of Proopiomelanocortin Neurons in Female Mice
por: Stincic, Todd L., et al.
Publicado: (2018)

Central anorexigenic actions of bile acids are mediated by TGR5
por: Perino, Alessia, et al.
Publicado: (2021)

Correction: An obesogenic feedforward loop involving PPARγ, acyl-CoA binding protein and GABA receptor
por: Anagnostopoulos, Gerasimos, et al.
Publicado: (2022)

An obesogenic feedforward loop involving PPARγ, acyl-CoA binding protein and GABA(A) receptor
por: Anagnostopoulos, Gerasimos, et al.
Publicado: (2022)

Reduced plasma level of diazepam-binding inhibitor (DBI) in patients with morbid obesity
por: Siejka, Agnieszka, et al.
Publicado: (2015)

Molecular, Cellular and Physiological Evidences for the Anorexigenic Actions of Nesfatin-1 in Goldfish
por: Gonzalez, Ronald, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_affud93u19jvkk289rt2l1jv52