Structural Modification of Nanomicelles through Phosphatidylcholine: The Enhanced Drug-Loading Capacity and Anticancer Activity of Celecoxib-Casein Nanoparticles for the Intravenous Delivery of Celecoxib

This study aims to stabilize loaded celecoxib (CX) by modifying the structure of casein nanoparticles through phosphatidylcholine. The results show that Egg yolk phosphatidylcholine PC(98T) (PC) significantly increased the stability of CX-PC-casein nanoparticles (NPs) (192.6 nm) from 5 min (CX-β-cas...

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Detalles Bibliográficos
Autores principales: Xv, Liuli, Qian, Xinxin, Wang, Yan, Yu, Chenghuan, Qin, Dingkui, Zhang, Yahui, Jin, Peng, Du, Qizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153595/
https://www.ncbi.nlm.nih.gov/pubmed/32131561
http://dx.doi.org/10.3390/nano10030451

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