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Hepato(Geno)Toxicity Assessment of Nanoparticles in a HepG2 Liver Spheroid Model
(1) In compliance with the 3Rs policy to reduce, refine and replace animal experiments, the development of advanced in vitro models is needed for nanotoxicity assessment. Cells cultivated in 3D resemble organ structures better than 2D cultures. This study aims to compare cytotoxic and genotoxic resp...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153628/ https://www.ncbi.nlm.nih.gov/pubmed/32197356 http://dx.doi.org/10.3390/nano10030545 |