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Liver Resection as Part of Cytoreductive Surgery for Ovarian Cancer

Objective: The aim of this study was to describe and evaluate the safety of hepatic resections for ovarian cancer liver metastases and the benefit in terms of survival as part of cytoreductive surgery among peritoneal seeding and parenchymal metastases. Materials and Methods: Data were reviewed retr...

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Autores principales: Luna-Abanto, Jorge, García Ruiz, Luis, Laura Martinez, Jheff, Álvarez Larraondo, Manuel, Villoslada Terrones, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153635/
https://www.ncbi.nlm.nih.gov/pubmed/32292262
http://dx.doi.org/10.1089/gyn.2019.0074
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author Luna-Abanto, Jorge
García Ruiz, Luis
Laura Martinez, Jheff
Álvarez Larraondo, Manuel
Villoslada Terrones, Vladimir
author_facet Luna-Abanto, Jorge
García Ruiz, Luis
Laura Martinez, Jheff
Álvarez Larraondo, Manuel
Villoslada Terrones, Vladimir
author_sort Luna-Abanto, Jorge
collection PubMed
description Objective: The aim of this study was to describe and evaluate the safety of hepatic resections for ovarian cancer liver metastases and the benefit in terms of survival as part of cytoreductive surgery among peritoneal seeding and parenchymal metastases. Materials and Methods: Data were reviewed retrospectively from patients who underwent liver resection as part of cytoreductive surgery for ovarian cancer at the Instituto Nacional de Enfermedades Neoplásicas, in Lima, Perú, from January 2009 to December 2017. Results: From January 2009 to December 2017, 1211 patients underwent surgical cytoreduction for ovarian cancer; 39 of these patients had liver resection as part of their surgical treatment, with 9, 17, and 13 patients receiving primary, secondary, and tertiary, resections, respectively. The mean age of the patients was 46, the majority (87%) had stage III/IV ovarian cancer. In addition, 21 patients had parenchymal metastasis resections, and 95% of the patients had Dindo–Clavien I and II grade complications. The 30-day mortality rate was 0. Conclusions: Liver resection for advanced ovarian cancer is a safe procedure for primary up to quaternary cytoreduction and may confer survival benefits to patients.
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spelling pubmed-71536352020-04-14 Liver Resection as Part of Cytoreductive Surgery for Ovarian Cancer Luna-Abanto, Jorge García Ruiz, Luis Laura Martinez, Jheff Álvarez Larraondo, Manuel Villoslada Terrones, Vladimir J Gynecol Surg Original Articles Objective: The aim of this study was to describe and evaluate the safety of hepatic resections for ovarian cancer liver metastases and the benefit in terms of survival as part of cytoreductive surgery among peritoneal seeding and parenchymal metastases. Materials and Methods: Data were reviewed retrospectively from patients who underwent liver resection as part of cytoreductive surgery for ovarian cancer at the Instituto Nacional de Enfermedades Neoplásicas, in Lima, Perú, from January 2009 to December 2017. Results: From January 2009 to December 2017, 1211 patients underwent surgical cytoreduction for ovarian cancer; 39 of these patients had liver resection as part of their surgical treatment, with 9, 17, and 13 patients receiving primary, secondary, and tertiary, resections, respectively. The mean age of the patients was 46, the majority (87%) had stage III/IV ovarian cancer. In addition, 21 patients had parenchymal metastasis resections, and 95% of the patients had Dindo–Clavien I and II grade complications. The 30-day mortality rate was 0. Conclusions: Liver resection for advanced ovarian cancer is a safe procedure for primary up to quaternary cytoreduction and may confer survival benefits to patients. Mary Ann Liebert, Inc., publishers 2020-04-01 2020-03-31 /pmc/articles/PMC7153635/ /pubmed/32292262 http://dx.doi.org/10.1089/gyn.2019.0074 Text en © Jorge Luna-Abanto et al. 2020; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Luna-Abanto, Jorge
García Ruiz, Luis
Laura Martinez, Jheff
Álvarez Larraondo, Manuel
Villoslada Terrones, Vladimir
Liver Resection as Part of Cytoreductive Surgery for Ovarian Cancer
title Liver Resection as Part of Cytoreductive Surgery for Ovarian Cancer
title_full Liver Resection as Part of Cytoreductive Surgery for Ovarian Cancer
title_fullStr Liver Resection as Part of Cytoreductive Surgery for Ovarian Cancer
title_full_unstemmed Liver Resection as Part of Cytoreductive Surgery for Ovarian Cancer
title_short Liver Resection as Part of Cytoreductive Surgery for Ovarian Cancer
title_sort liver resection as part of cytoreductive surgery for ovarian cancer
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153635/
https://www.ncbi.nlm.nih.gov/pubmed/32292262
http://dx.doi.org/10.1089/gyn.2019.0074
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