Large Vessel Vasculitis as a Possible Mechanism of Vascular Side Effects of Ponatinib: A Case Report

Arterial occlusive events (AOEs) such as cerebrovascular, cardiovascular and peripheral arterial events are known side effects of ponatinib, assumed due to the rapid development and increase of arteriosclerosis, while the definitive pathomechanisms therefore are still unclear. We present a case of c...

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Autores principales: Hirschbuehl, Klaus, Rank, Andreas, Pfeiffer, Tim, Schaller, Tina, Haeckel, Thomas, Roeling, Joerg, Vlasenko, Dmytro, Trepel, Martin, Schmid, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153681/
https://www.ncbi.nlm.nih.gov/pubmed/32300450
http://dx.doi.org/10.14740/jh519
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author Hirschbuehl, Klaus
Rank, Andreas
Pfeiffer, Tim
Schaller, Tina
Haeckel, Thomas
Roeling, Joerg
Vlasenko, Dmytro
Trepel, Martin
Schmid, Christoph
author_facet Hirschbuehl, Klaus
Rank, Andreas
Pfeiffer, Tim
Schaller, Tina
Haeckel, Thomas
Roeling, Joerg
Vlasenko, Dmytro
Trepel, Martin
Schmid, Christoph
author_sort Hirschbuehl, Klaus
collection PubMed
description Arterial occlusive events (AOEs) such as cerebrovascular, cardiovascular and peripheral arterial events are known side effects of ponatinib, assumed due to the rapid development and increase of arteriosclerosis, while the definitive pathomechanisms therefore are still unclear. We present a case of clinically apparent large vessel vasculitis and discuss this phenomenon as a possible mechanism of AOEs beside arteriosclerosis.
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spelling pubmed-71536812020-04-16 Large Vessel Vasculitis as a Possible Mechanism of Vascular Side Effects of Ponatinib: A Case Report Hirschbuehl, Klaus Rank, Andreas Pfeiffer, Tim Schaller, Tina Haeckel, Thomas Roeling, Joerg Vlasenko, Dmytro Trepel, Martin Schmid, Christoph J Hematol Case Report Arterial occlusive events (AOEs) such as cerebrovascular, cardiovascular and peripheral arterial events are known side effects of ponatinib, assumed due to the rapid development and increase of arteriosclerosis, while the definitive pathomechanisms therefore are still unclear. We present a case of clinically apparent large vessel vasculitis and discuss this phenomenon as a possible mechanism of AOEs beside arteriosclerosis. Elmer Press 2019-06 2019-06-30 /pmc/articles/PMC7153681/ /pubmed/32300450 http://dx.doi.org/10.14740/jh519 Text en Copyright 2019, Hirschbuehl et al. http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Hirschbuehl, Klaus
Rank, Andreas
Pfeiffer, Tim
Schaller, Tina
Haeckel, Thomas
Roeling, Joerg
Vlasenko, Dmytro
Trepel, Martin
Schmid, Christoph
Large Vessel Vasculitis as a Possible Mechanism of Vascular Side Effects of Ponatinib: A Case Report
title Large Vessel Vasculitis as a Possible Mechanism of Vascular Side Effects of Ponatinib: A Case Report
title_full Large Vessel Vasculitis as a Possible Mechanism of Vascular Side Effects of Ponatinib: A Case Report
title_fullStr Large Vessel Vasculitis as a Possible Mechanism of Vascular Side Effects of Ponatinib: A Case Report
title_full_unstemmed Large Vessel Vasculitis as a Possible Mechanism of Vascular Side Effects of Ponatinib: A Case Report
title_short Large Vessel Vasculitis as a Possible Mechanism of Vascular Side Effects of Ponatinib: A Case Report
title_sort large vessel vasculitis as a possible mechanism of vascular side effects of ponatinib: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153681/
https://www.ncbi.nlm.nih.gov/pubmed/32300450
http://dx.doi.org/10.14740/jh519
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