Cargando…

The quest to identify the mechanism underlying adrenergic regulation of cardiac Ca(2+) channels

Activation of protein kinase A by cyclic AMP results in a multi-fold upregulation of Ca(V)1.2 currents in the heart, as originally reported in the 1970's and 1980's. Despite considerable interest and much investment, the molecular mechanisms responsible for this signature modulation remain...

Descripción completa

Detalles Bibliográficos
Autores principales: Roybal, Daniel, Hennessey, Jessica A., Marx, Steven O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153787/
https://www.ncbi.nlm.nih.gov/pubmed/32195622
http://dx.doi.org/10.1080/19336950.2020.1740502