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The quest to identify the mechanism underlying adrenergic regulation of cardiac Ca(2+) channels
Activation of protein kinase A by cyclic AMP results in a multi-fold upregulation of Ca(V)1.2 currents in the heart, as originally reported in the 1970's and 1980's. Despite considerable interest and much investment, the molecular mechanisms responsible for this signature modulation remain...
Autores principales: | Roybal, Daniel, Hennessey, Jessica A., Marx, Steven O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153787/ https://www.ncbi.nlm.nih.gov/pubmed/32195622 http://dx.doi.org/10.1080/19336950.2020.1740502 |
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