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Obtaining transition rates from single-channel data without initial parameter seeding

Background and Purpose: Ion-channels are membrane proteins that can adopt several distinct structural conformations. Some of the conformations are open and allow the passage of ions through the membrane; others are closed and hinder ion flow. Patch-clamp recordings of single ion-channels show if a c...

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Detalles Bibliográficos
Autor principal: Voldsgaard Clausen, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153788/
https://www.ncbi.nlm.nih.gov/pubmed/32108549
http://dx.doi.org/10.1080/19336950.2020.1732004