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Regulation of the cold-sensing TRPM8 channels by phosphoinositides and G(q)-coupled receptors
The Transient Receptor Potential Melastatin 8 (TRPM8) ion channel is an important sensor of environmental cold temperatures. Cold- and menthol-induced activation of this channel requires the presence of the membrane phospholipid phosphatidylinositol 4,5-bisphosphate [PI(4,5)P(2)]. This review discus...
Autores principales: | Liu, Luyu, Rohacs, Tibor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153793/ https://www.ncbi.nlm.nih.gov/pubmed/32101066 http://dx.doi.org/10.1080/19336950.2020.1734266 |
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