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Regulation of the cold-sensing TRPM8 channels by phosphoinositides and G(q)-coupled receptors

The Transient Receptor Potential Melastatin 8 (TRPM8) ion channel is an important sensor of environmental cold temperatures. Cold- and menthol-induced activation of this channel requires the presence of the membrane phospholipid phosphatidylinositol 4,5-bisphosphate [PI(4,5)P(2)]. This review discus...

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Detalles Bibliográficos
Autores principales: Liu, Luyu, Rohacs, Tibor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153793/
https://www.ncbi.nlm.nih.gov/pubmed/32101066
http://dx.doi.org/10.1080/19336950.2020.1734266

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