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HX008: a humanized PD-1 blocking antibody with potent antitumor activity and superior pharmacologic properties
Through reactivating tumor-infiltrating lymphocytes, therapeutics targeting programmed cell death protein 1 (PD-1) demonstrate impressive clinical efficacy in the treatment of multiple cancers. In this report, we characterize HX008, a humanized IgG4S228P anti-PD-1 monoclonal antibody with an enginee...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153830/ https://www.ncbi.nlm.nih.gov/pubmed/32106752 http://dx.doi.org/10.1080/19420862.2020.1724751 |