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Interaction analysis of glycoengineered antibodies with CD16a: a native mass spectrometry approach

Minor changes in the quality of biologically manufactured monoclonal antibodies (mAbs) can affect their bioactivity and efficacy. One of the most important variations concerns the N-glycosylation pattern, which directly affects an anti-tumor mechanism called antibody-dependent cell-meditated cytotox...

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Detalles Bibliográficos
Autores principales: Hajduk, Joanna, Brunner, Cyrill, Malik, Sebastian, Bangerter, Jana, Schneider, Gisbert, Thomann, Marco, Reusch, Dietmar, Zenobi, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153833/
https://www.ncbi.nlm.nih.gov/pubmed/32167012
http://dx.doi.org/10.1080/19420862.2020.1736975