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Interaction analysis of glycoengineered antibodies with CD16a: a native mass spectrometry approach
Minor changes in the quality of biologically manufactured monoclonal antibodies (mAbs) can affect their bioactivity and efficacy. One of the most important variations concerns the N-glycosylation pattern, which directly affects an anti-tumor mechanism called antibody-dependent cell-meditated cytotox...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153833/ https://www.ncbi.nlm.nih.gov/pubmed/32167012 http://dx.doi.org/10.1080/19420862.2020.1736975 |