Cargando…
Intein mediated high throughput screening for bispecific antibodies
Bispecific antibodies comprise extremely diverse architectures enabling complex modes of action, such as effector cell recruitment or conditional target modulation via dual targeting, not conveyed by monospecific antibodies. In recent years, research on bispecific therapeutics has substantially grow...
Autores principales: | Hofmann, Tim, Schmidt, Johannes, Ciesielski, Elke, Becker, Stefan, Rysiok, Thomas, Schütte, Mark, Toleikis, Lars, Kolmar, Harald, Doerner, Achim |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153837/ https://www.ncbi.nlm.nih.gov/pubmed/32151188 http://dx.doi.org/10.1080/19420862.2020.1731938 |
Ejemplares similares
-
Greatest Hits—Innovative Technologies for High Throughput Identification of Bispecific Antibodies
por: Hofmann, Tim, et al.
Publicado: (2020) -
Selection of Antibodies with Tailored Properties by Application of High-Throughput Multiparameter Fluorescence-Activated Cell Sorting of Yeast-Displayed Immune Libraries
por: Schröter, Christian, et al.
Publicado: (2018) -
Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibition
por: Lipinski, Britta, et al.
Publicado: (2023) -
Beyond bispecificity: Controlled Fab arm exchange for the generation of antibodies with multiple specificities
por: Yanakieva, Desislava, et al.
Publicado: (2022) -
Engineering IgG-Like Bispecific Antibodies—An Overview
por: Krah, Simon, et al.
Publicado: (2018)