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An innovative plasmacytoid dendritic cell line-based cancer vaccine primes and expands antitumor T-cells in melanoma patients in a first-in-human trial
The efficacy of immune checkpoint inhibitors has been shown to depend on preexisting antitumor immunity; thus, their combination with cancer vaccines is an attractive therapeutic approach. Plasmacytoid dendritic cells (PDC) are strong inducers of antitumor responses and represent promising vaccine c...
Autores principales: | Charles, Julie, Chaperot, Laurence, Hannani, Dalil, Bruder Costa, Juliana, Templier, Isabelle, Trabelsi, Sabiha, Gil, Hugo, Moisan, Anaick, Persoons, Virginie, Hegelhofer, Harald, Schir, Edith, Quesada, Jean-Louis, Mendoza, Christophe, Aspord, Caroline, Manches, Olivier, Coulie, Pierre G., Khammari, Amir, Dreno, Brigitte, Leccia, Marie-Thérèse, Plumas, Joel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153838/ https://www.ncbi.nlm.nih.gov/pubmed/32313721 http://dx.doi.org/10.1080/2162402X.2020.1738812 |
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