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Predicting Antibody Developability Profiles Through Early Stage Discovery Screening
Monoclonal antibodies play an increasingly important role for the development of new drugs across multiple therapy areas. The term ‘developability’ encompasses the feasibility of molecules to successfully progress from discovery to development via evaluation of their physicochemical properties. Thes...
Autores principales: | Bailly, Marc, Mieczkowski, Carl, Juan, Veronica, Metwally, Essam, Tomazela, Daniela, Baker, Jeanne, Uchida, Makiko, Kofman, Ester, Raoufi, Fahimeh, Motlagh, Soha, Yu, Yao, Park, Jihea, Raghava, Smita, Welsh, John, Rauscher, Michael, Raghunathan, Gopalan, Hsieh, Mark, Chen, Yi-Ling, Nguyen, Hang Thu, Nguyen, Nhung, Cipriano, Dan, Fayadat-Dilman, Laurence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153844/ https://www.ncbi.nlm.nih.gov/pubmed/32249670 http://dx.doi.org/10.1080/19420862.2020.1743053 |
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