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High throughput screening and identification of coagulopathic snake venom proteins and peptides using nanofractionation and proteomics approaches
Snakebite is a neglected tropical disease that results in a variety of systemic and local pathologies in envenomed victims and is responsible for around 138,000 deaths every year. Many snake venoms cause severe coagulopathy that makes victims vulnerable to suffering life-threating haemorrhage. The m...
Autores principales: | Slagboom, Julien, Mladić, Marija, Xie, Chunfang, Kazandjian, Taline D., Vonk, Freek, Somsen, Govert W., Casewell, Nicholas R., Kool, Jeroen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153897/ https://www.ncbi.nlm.nih.gov/pubmed/32236099 http://dx.doi.org/10.1371/journal.pntd.0007802 |
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