Sustained perfusion of revascularized bioengineered livers heterotopically transplanted into immunosuppressed pigs

Implanted bioengineered livers have not exceeded three days of continuous perfusion. Here, we show that decellularized whole porcine livers revascularized with human umbilical endothelial cells and implanted heterotopically into immunosuppressed pigs whose spleen has been removed can sustain perfusi...

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Detalles Bibliográficos
Autores principales: Shaheen, Mohammed F., Joo, DongJin, Ross, Jeffrey J., Anderson, Brett D., Chen, Harvey S., Huebert, Robert C., Li, Yi, Amiot, Bruce, Young, Anne, Zlochiver, Viviana, Nelson, Erek, Mounajjed, Taofic, Dietz, Allan B., Michalak, Gregory, Steiner, Benjamin G., Davidow, Dominique Seetapun, Paradise, Christopher R., van Wijnen, Andre J., Shah, Vijay H., Liu, Mengfei, Nyberg, Scott L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7153989/
https://www.ncbi.nlm.nih.gov/pubmed/31611679
http://dx.doi.org/10.1038/s41551-019-0460-x

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