Pharmacokinetics, Safety, and Preliminary Efficacy of Oral Trifluridine/Tipiracil in Chinese Patients with Solid Tumors: A Phase 1b, Open-Label Study

PURPOSE: Trifluridine/tipiracil (FTD/TPI) is approved in Japan, the United States (US), and Europe for metastatic colorectal cancer (mCRC) refractory to standard therapies. This Phase 1b open-label study focused on the pharmacokinetic (PK) and toxicity profiles of FTD/TPI in Chinese patients with so...

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Detalles Bibliográficos
Autores principales: Wang, Xicheng, Zhou, Jianfeng, Li, Yan, Ge, Yuping, Zhou, Yanping, Bai, Chunmei, Shen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154008/
https://www.ncbi.nlm.nih.gov/pubmed/32308505
http://dx.doi.org/10.2147/CPAA.S232104

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