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Novel Human Polymorphisms Define a Key Role for the SLC26A6-STAS Domain in Protection From Ca(2+)-Oxalate Lithogenesis
Impaired homeostasis of the carboxylic acids oxalate and citrate, dramatically increases the risk for the formation of Ca(2+)-oxalate kidney stones, which is the most common form of kidney stones in humans. Renal homeostasis of oxalate and citrate is controlled by complex mechanisms including epithe...
Autores principales: | Shimshilashvili, Liana, Aharon, Sara, Moe, Orson W., Ohana, Ehud |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154107/ https://www.ncbi.nlm.nih.gov/pubmed/32317970 http://dx.doi.org/10.3389/fphar.2020.00405 |
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