Development of Quantitative Methylation-Specific Droplet Digital PCR (ddMSP) for Assessment of Natural Tregs

Regulatory T cells (Tregs) suppress immune responses in vivo in an antigen-specific manner. Of clinical relevance, Tregs can be isolated and expanded in vitro while maintaining immunoregulatory function. Tregs are classified as CD4(+)CD25(high)CD127(low) FOXP3(+) cells. Demethylation of the Treg-spe...

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Detalles Bibliográficos
Autores principales: Husseiny, Mohamed I., Fahmy, Ahmed, Du, Weiting, Gu, Angel, Garcia, Pablo, Ferreri, Kevin, Kandeel, Fouad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154152/
https://www.ncbi.nlm.nih.gov/pubmed/32318096
http://dx.doi.org/10.3389/fgene.2020.00300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154152/
https://www.ncbi.nlm.nih.gov/pubmed/32318096
http://dx.doi.org/10.3389/fgene.2020.00300

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