Cargando…

Targeted Radiotherapy of the Tumor Cavity after Surgical Resection of Aggressive Recurrent Brain Metastasis: A Case Report

Postoperative management of patients with brain metastases is controversial. Besides local control, cognitive function and quality of life are the most important outcomes of postoperative radiotherapy. In this case report, we introduce a patient with aggressive recurred solid metastasis treated with...

Descripción completa

Detalles Bibliográficos
Autores principales: Fadrus, Pavel, Kazda, Tomas, Dvoracek, Petr, Pospisil, Petr, Hynkova, Ludmila, Zitterbartova, Jana, Dymackova, Radana, Kolouskova, Ivana, Belanova, Renata, Prochazka, Tomas, Slampa, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154243/
https://www.ncbi.nlm.nih.gov/pubmed/32308582
http://dx.doi.org/10.1159/000506328
_version_ 1783521789947674624
author Fadrus, Pavel
Kazda, Tomas
Dvoracek, Petr
Pospisil, Petr
Hynkova, Ludmila
Zitterbartova, Jana
Dymackova, Radana
Kolouskova, Ivana
Belanova, Renata
Prochazka, Tomas
Slampa, Pavel
author_facet Fadrus, Pavel
Kazda, Tomas
Dvoracek, Petr
Pospisil, Petr
Hynkova, Ludmila
Zitterbartova, Jana
Dymackova, Radana
Kolouskova, Ivana
Belanova, Renata
Prochazka, Tomas
Slampa, Pavel
author_sort Fadrus, Pavel
collection PubMed
description Postoperative management of patients with brain metastases is controversial. Besides local control, cognitive function and quality of life are the most important outcomes of postoperative radiotherapy. In this case report, we introduce a patient with aggressive recurred solid metastasis treated with repeated surgery and an individual radiotherapy approach in order to highlight that close mutual collaboration leads to a clear benefit for our patients. The local targeted radiotherapy with 35 Gy in 10 fractions was performed with the volumetric modulated arc technique, leading to more than 2.5 years of local control and survival without any of the side effects usually attributed to whole brain radiotherapy.
format Online
Article
Text
id pubmed-7154243
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher S. Karger AG
record_format MEDLINE/PubMed
spelling pubmed-71542432020-04-19 Targeted Radiotherapy of the Tumor Cavity after Surgical Resection of Aggressive Recurrent Brain Metastasis: A Case Report Fadrus, Pavel Kazda, Tomas Dvoracek, Petr Pospisil, Petr Hynkova, Ludmila Zitterbartova, Jana Dymackova, Radana Kolouskova, Ivana Belanova, Renata Prochazka, Tomas Slampa, Pavel Case Rep Oncol Case Report Postoperative management of patients with brain metastases is controversial. Besides local control, cognitive function and quality of life are the most important outcomes of postoperative radiotherapy. In this case report, we introduce a patient with aggressive recurred solid metastasis treated with repeated surgery and an individual radiotherapy approach in order to highlight that close mutual collaboration leads to a clear benefit for our patients. The local targeted radiotherapy with 35 Gy in 10 fractions was performed with the volumetric modulated arc technique, leading to more than 2.5 years of local control and survival without any of the side effects usually attributed to whole brain radiotherapy. S. Karger AG 2020-03-19 /pmc/articles/PMC7154243/ /pubmed/32308582 http://dx.doi.org/10.1159/000506328 Text en Copyright © 2020 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Fadrus, Pavel
Kazda, Tomas
Dvoracek, Petr
Pospisil, Petr
Hynkova, Ludmila
Zitterbartova, Jana
Dymackova, Radana
Kolouskova, Ivana
Belanova, Renata
Prochazka, Tomas
Slampa, Pavel
Targeted Radiotherapy of the Tumor Cavity after Surgical Resection of Aggressive Recurrent Brain Metastasis: A Case Report
title Targeted Radiotherapy of the Tumor Cavity after Surgical Resection of Aggressive Recurrent Brain Metastasis: A Case Report
title_full Targeted Radiotherapy of the Tumor Cavity after Surgical Resection of Aggressive Recurrent Brain Metastasis: A Case Report
title_fullStr Targeted Radiotherapy of the Tumor Cavity after Surgical Resection of Aggressive Recurrent Brain Metastasis: A Case Report
title_full_unstemmed Targeted Radiotherapy of the Tumor Cavity after Surgical Resection of Aggressive Recurrent Brain Metastasis: A Case Report
title_short Targeted Radiotherapy of the Tumor Cavity after Surgical Resection of Aggressive Recurrent Brain Metastasis: A Case Report
title_sort targeted radiotherapy of the tumor cavity after surgical resection of aggressive recurrent brain metastasis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154243/
https://www.ncbi.nlm.nih.gov/pubmed/32308582
http://dx.doi.org/10.1159/000506328
work_keys_str_mv AT fadruspavel targetedradiotherapyofthetumorcavityaftersurgicalresectionofaggressiverecurrentbrainmetastasisacasereport
AT kazdatomas targetedradiotherapyofthetumorcavityaftersurgicalresectionofaggressiverecurrentbrainmetastasisacasereport
AT dvoracekpetr targetedradiotherapyofthetumorcavityaftersurgicalresectionofaggressiverecurrentbrainmetastasisacasereport
AT pospisilpetr targetedradiotherapyofthetumorcavityaftersurgicalresectionofaggressiverecurrentbrainmetastasisacasereport
AT hynkovaludmila targetedradiotherapyofthetumorcavityaftersurgicalresectionofaggressiverecurrentbrainmetastasisacasereport
AT zitterbartovajana targetedradiotherapyofthetumorcavityaftersurgicalresectionofaggressiverecurrentbrainmetastasisacasereport
AT dymackovaradana targetedradiotherapyofthetumorcavityaftersurgicalresectionofaggressiverecurrentbrainmetastasisacasereport
AT kolouskovaivana targetedradiotherapyofthetumorcavityaftersurgicalresectionofaggressiverecurrentbrainmetastasisacasereport
AT belanovarenata targetedradiotherapyofthetumorcavityaftersurgicalresectionofaggressiverecurrentbrainmetastasisacasereport
AT prochazkatomas targetedradiotherapyofthetumorcavityaftersurgicalresectionofaggressiverecurrentbrainmetastasisacasereport
AT slampapavel targetedradiotherapyofthetumorcavityaftersurgicalresectionofaggressiverecurrentbrainmetastasisacasereport