A Case of Large Sarcoid Choroidal Granuloma Treated with Steroid Pulse Therapy

PURPOSE: To report a case of large sarcoid choroidal granuloma that was successfully treated with steroid pulse therapy. CASE REPORT: A 38-year-old man presented with the primary complaint of decreased visual acuity (VA) in his left eye. Upon examination, a large white protruding lesion of 10 × 8 pa...

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Autores principales: Kobayashi, Takatoshi, Takai, Nanae, Sato, Takaki, Tada, Rei, Maruyama, Eri, Shouda, Hiromi, Okamoto, Takako, Maruyama, Kohichi, Ikeda, Tsunehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154259/
https://www.ncbi.nlm.nih.gov/pubmed/32308612
http://dx.doi.org/10.1159/000506437
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author Kobayashi, Takatoshi
Takai, Nanae
Sato, Takaki
Tada, Rei
Maruyama, Eri
Shouda, Hiromi
Okamoto, Takako
Maruyama, Kohichi
Ikeda, Tsunehiko
author_facet Kobayashi, Takatoshi
Takai, Nanae
Sato, Takaki
Tada, Rei
Maruyama, Eri
Shouda, Hiromi
Okamoto, Takako
Maruyama, Kohichi
Ikeda, Tsunehiko
author_sort Kobayashi, Takatoshi
collection PubMed
description PURPOSE: To report a case of large sarcoid choroidal granuloma that was successfully treated with steroid pulse therapy. CASE REPORT: A 38-year-old man presented with the primary complaint of decreased visual acuity (VA) in his left eye. Upon examination, a large white protruding lesion of 10 × 8 papilla diameter in size was observed in the macular region, and slightly temporal to it, in the patient's left eye. Whole-body contrast-enhanced computed tomography performed for differential diagnosis detected numerous enlarged lymph nodes throughout the body, including the bilateral hilar regions. Sarcoidosis was diagnosed by biopsy of the right cervical lymph nodes showing noncaseating epithelioid cell granuloma. The fundus lesion was found to be a choroidal granuloma caused by sarcoidosis, and steroid pulse therapy was started. The granuloma was considerably decreased, and the VA in the left eye improved to 0.7 after 2 months. CONCLUSION: Steroid pulse therapy was found to be effective as an initial treatment for a large sarcoid choroidal granuloma.
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spelling pubmed-71542592020-04-19 A Case of Large Sarcoid Choroidal Granuloma Treated with Steroid Pulse Therapy Kobayashi, Takatoshi Takai, Nanae Sato, Takaki Tada, Rei Maruyama, Eri Shouda, Hiromi Okamoto, Takako Maruyama, Kohichi Ikeda, Tsunehiko Case Rep Ophthalmol Case Report PURPOSE: To report a case of large sarcoid choroidal granuloma that was successfully treated with steroid pulse therapy. CASE REPORT: A 38-year-old man presented with the primary complaint of decreased visual acuity (VA) in his left eye. Upon examination, a large white protruding lesion of 10 × 8 papilla diameter in size was observed in the macular region, and slightly temporal to it, in the patient's left eye. Whole-body contrast-enhanced computed tomography performed for differential diagnosis detected numerous enlarged lymph nodes throughout the body, including the bilateral hilar regions. Sarcoidosis was diagnosed by biopsy of the right cervical lymph nodes showing noncaseating epithelioid cell granuloma. The fundus lesion was found to be a choroidal granuloma caused by sarcoidosis, and steroid pulse therapy was started. The granuloma was considerably decreased, and the VA in the left eye improved to 0.7 after 2 months. CONCLUSION: Steroid pulse therapy was found to be effective as an initial treatment for a large sarcoid choroidal granuloma. S. Karger AG 2020-03-11 /pmc/articles/PMC7154259/ /pubmed/32308612 http://dx.doi.org/10.1159/000506437 Text en Copyright © 2020 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Kobayashi, Takatoshi
Takai, Nanae
Sato, Takaki
Tada, Rei
Maruyama, Eri
Shouda, Hiromi
Okamoto, Takako
Maruyama, Kohichi
Ikeda, Tsunehiko
A Case of Large Sarcoid Choroidal Granuloma Treated with Steroid Pulse Therapy
title A Case of Large Sarcoid Choroidal Granuloma Treated with Steroid Pulse Therapy
title_full A Case of Large Sarcoid Choroidal Granuloma Treated with Steroid Pulse Therapy
title_fullStr A Case of Large Sarcoid Choroidal Granuloma Treated with Steroid Pulse Therapy
title_full_unstemmed A Case of Large Sarcoid Choroidal Granuloma Treated with Steroid Pulse Therapy
title_short A Case of Large Sarcoid Choroidal Granuloma Treated with Steroid Pulse Therapy
title_sort case of large sarcoid choroidal granuloma treated with steroid pulse therapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154259/
https://www.ncbi.nlm.nih.gov/pubmed/32308612
http://dx.doi.org/10.1159/000506437
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