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Prolyl endopeptidase gene disruption attenuates high fat diet-induced nonalcoholic fatty liver disease in mice by improving hepatic steatosis and inflammation

BACKGROUND: Prolyl endopeptidase (PREP) is a serine endopeptidase that regulates inflammatory responses. PREP inhibitors can reduce hepatocyte lipid accumulation and may participate in the progression of nonalcoholic fatty liver disease (NAFLD). We investigated whether disruption of PREP regulates h...

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Detalles Bibliográficos
Autores principales:	Jiang, Dai-Xi, Zhang, Jian-Bin, Li, Meng-Ting, Lin, Shuang-Zhe, Wang, Yu-Qin, Chen, Yuan-Wen, Fan, Jian-Gao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154388/ https://www.ncbi.nlm.nih.gov/pubmed/32309365 http://dx.doi.org/10.21037/atm.2020.01.14

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