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Cyclic helix B peptide ameliorates renal tubulointerstitial fibrosis induced by unilateral ureter obstruction via inhibiting NLRP3 pathway
BACKGROUND: Renal fibrosis is the inevitable outcome of all progressive chronic kidney diseases (CKD) and leads to a gradual loss of renal function. We previously reported cyclic helix B peptide (CHBP), a novel synthesized peptide derived from erythropoietin, had shown effective renoprotection. In t...
Autores principales: | Qi, Ruochen, Zhang, Weitao, Zheng, Long, Xu, Ming, Rong, Ruiming, Zhu, Tongyu, Yang, Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154394/ https://www.ncbi.nlm.nih.gov/pubmed/32309314 http://dx.doi.org/10.21037/atm.2020.02.12 |
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