Breaking the Enigma Code of Angiotensin II Type 2 Receptor Signaling

In this issue of Structure, Asada et al. (2019) present angiotensin receptor AT(2)R structure in complex with its main endogenous agonist, AngII peptide. Complementing the previous structural studies, the new complex structure sheds light on the AT(2)R activation mechanism and opens new avenues for...

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Detalles Bibliográficos
Autores principales: Sadybekov, Anastasiia, Katritch, Vsevolod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154512/
https://www.ncbi.nlm.nih.gov/pubmed/32268077
http://dx.doi.org/10.1016/j.str.2020.03.004
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author Sadybekov, Anastasiia
Katritch, Vsevolod
author_facet Sadybekov, Anastasiia
Katritch, Vsevolod
author_sort Sadybekov, Anastasiia
collection PubMed
description In this issue of Structure, Asada et al. (2019) present angiotensin receptor AT(2)R structure in complex with its main endogenous agonist, AngII peptide. Complementing the previous structural studies, the new complex structure sheds light on the AT(2)R activation mechanism and opens new avenues for drug discovery targeting this enigmatic receptor.
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spelling pubmed-71545122020-04-14 Breaking the Enigma Code of Angiotensin II Type 2 Receptor Signaling Sadybekov, Anastasiia Katritch, Vsevolod Structure Article In this issue of Structure, Asada et al. (2019) present angiotensin receptor AT(2)R structure in complex with its main endogenous agonist, AngII peptide. Complementing the previous structural studies, the new complex structure sheds light on the AT(2)R activation mechanism and opens new avenues for drug discovery targeting this enigmatic receptor. Elsevier Ltd. 2020-04-07 2020-04-07 /pmc/articles/PMC7154512/ /pubmed/32268077 http://dx.doi.org/10.1016/j.str.2020.03.004 Text en © 2020 Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Sadybekov, Anastasiia
Katritch, Vsevolod
Breaking the Enigma Code of Angiotensin II Type 2 Receptor Signaling
title Breaking the Enigma Code of Angiotensin II Type 2 Receptor Signaling
title_full Breaking the Enigma Code of Angiotensin II Type 2 Receptor Signaling
title_fullStr Breaking the Enigma Code of Angiotensin II Type 2 Receptor Signaling
title_full_unstemmed Breaking the Enigma Code of Angiotensin II Type 2 Receptor Signaling
title_short Breaking the Enigma Code of Angiotensin II Type 2 Receptor Signaling
title_sort breaking the enigma code of angiotensin ii type 2 receptor signaling
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154512/
https://www.ncbi.nlm.nih.gov/pubmed/32268077
http://dx.doi.org/10.1016/j.str.2020.03.004
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