Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China

An in-depth annotation of the newly discovered coronavirus (2019-nCoV) genome has revealed differences between 2019-nCoV and severe acute respiratory syndrome (SARS) or SARS-like coronaviruses. A systematic comparison identified 380 amino acid substitutions between these coronaviruses, which may hav...

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Autores principales: Wu, Aiping, Peng, Yousong, Huang, Baoying, Ding, Xiao, Wang, Xianyue, Niu, Peihua, Meng, Jing, Zhu, Zhaozhong, Zhang, Zheng, Wang, Jiangyuan, Sheng, Jie, Quan, Lijun, Xia, Zanxian, Tan, Wenjie, Cheng, Genhong, Jiang, Taijiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154514/
https://www.ncbi.nlm.nih.gov/pubmed/32035028
http://dx.doi.org/10.1016/j.chom.2020.02.001
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author Wu, Aiping
Peng, Yousong
Huang, Baoying
Ding, Xiao
Wang, Xianyue
Niu, Peihua
Meng, Jing
Zhu, Zhaozhong
Zhang, Zheng
Wang, Jiangyuan
Sheng, Jie
Quan, Lijun
Xia, Zanxian
Tan, Wenjie
Cheng, Genhong
Jiang, Taijiao
author_facet Wu, Aiping
Peng, Yousong
Huang, Baoying
Ding, Xiao
Wang, Xianyue
Niu, Peihua
Meng, Jing
Zhu, Zhaozhong
Zhang, Zheng
Wang, Jiangyuan
Sheng, Jie
Quan, Lijun
Xia, Zanxian
Tan, Wenjie
Cheng, Genhong
Jiang, Taijiao
author_sort Wu, Aiping
collection PubMed
description An in-depth annotation of the newly discovered coronavirus (2019-nCoV) genome has revealed differences between 2019-nCoV and severe acute respiratory syndrome (SARS) or SARS-like coronaviruses. A systematic comparison identified 380 amino acid substitutions between these coronaviruses, which may have caused functional and pathogenic divergence of 2019-nCoV.
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spelling pubmed-71545142020-04-14 Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China Wu, Aiping Peng, Yousong Huang, Baoying Ding, Xiao Wang, Xianyue Niu, Peihua Meng, Jing Zhu, Zhaozhong Zhang, Zheng Wang, Jiangyuan Sheng, Jie Quan, Lijun Xia, Zanxian Tan, Wenjie Cheng, Genhong Jiang, Taijiao Cell Host Microbe Commentary An in-depth annotation of the newly discovered coronavirus (2019-nCoV) genome has revealed differences between 2019-nCoV and severe acute respiratory syndrome (SARS) or SARS-like coronaviruses. A systematic comparison identified 380 amino acid substitutions between these coronaviruses, which may have caused functional and pathogenic divergence of 2019-nCoV. Elsevier Inc. 2020-03-11 2020-02-07 /pmc/articles/PMC7154514/ /pubmed/32035028 http://dx.doi.org/10.1016/j.chom.2020.02.001 Text en © 2020 Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Commentary
Wu, Aiping
Peng, Yousong
Huang, Baoying
Ding, Xiao
Wang, Xianyue
Niu, Peihua
Meng, Jing
Zhu, Zhaozhong
Zhang, Zheng
Wang, Jiangyuan
Sheng, Jie
Quan, Lijun
Xia, Zanxian
Tan, Wenjie
Cheng, Genhong
Jiang, Taijiao
Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China
title Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China
title_full Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China
title_fullStr Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China
title_full_unstemmed Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China
title_short Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China
title_sort genome composition and divergence of the novel coronavirus (2019-ncov) originating in china
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154514/
https://www.ncbi.nlm.nih.gov/pubmed/32035028
http://dx.doi.org/10.1016/j.chom.2020.02.001
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