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TLC388 Induces DNA Damage and G2 Phase Cell Cycle Arrest in Human Non-Small Cell Lung Cancer Cells

TLC388, a camptothecin-derivative targeting topoisomerase I, is a potential anticancer drug. In this study, its effect on A549 and H838 human non-small cell lung cancer (NSCLC) cells was investigated. Cell viability and proliferation were determined by thiazolyl blue tetrazolium bromide and clonogen...

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Detalles Bibliográficos
Autores principales:	Wu, Kun-Ming, Chi, Chih-Wen, Lai, Jerry Cheng-Yen, Chen, Yu-Jen, Kou, Yu Ru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2020
Materias:	Special Collection on Recent Advances in Cancer Prevention and Treatment
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154561/ https://www.ncbi.nlm.nih.gov/pubmed/32281394 http://dx.doi.org/10.1177/1073274819897975

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