Use of an Outbred Rat Hepacivirus Challenge Model for Design and Evaluation of Efficacy of Different Immunization Strategies for Hepatitis C Virus

BACKGROUND AND AIMS: The lack of immunocompetent small animal models for hepatitis C virus (HCV) has greatly hindered the development of effective vaccines. Using rodent hepacivirus (RHV), a homolog of HCV that shares many characteristics of HCV infection, we report the development and application o...

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Detalles Bibliográficos
Autores principales: Atcheson, Erwan, Li, Wenqin, Bliss, Carly M., Chinnakannan, Senthil, Heim, Kathrin, Sharpe, Hannah, Hutchings, Claire, Dietrich, Isabelle, Nguyen, Dung, Kapoor, Amit, Jarvis, Michael A., Klenerman, Paul, Barnes, Eleanor, Simmonds, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154631/
https://www.ncbi.nlm.nih.gov/pubmed/31400152
http://dx.doi.org/10.1002/hep.30894

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