4‐1BB Delineates Distinct Activation Status of Exhausted Tumor‐Infiltrating CD8(+) T Cells in Hepatocellular Carcinoma

BACKGROUND AND AIMS: Targeting costimulatory receptors with agonistic antibodies is a promising cancer immunotherapy option. We aimed to investigate costimulatory receptor expression, particularly 4‐1BB (CD137 or tumor necrosis factor receptor superfamily member 9), on tumor‐infiltrating CD8(+) T ce...

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Detalles Bibliográficos
Autores principales: Kim, Hyung‐Don, Park, Seongyeol, Jeong, Seongju, Lee, Yong Joon, Lee, Hoyoung, Kim, Chang Gon, Kim, Kyung Hwan, Hong, Seung‐Mo, Lee, Jung‐Yun, Kim, Sunghoon, Kim, Hong Kwan, Min, Byung Soh, Chang, Jong Hee, Ju, Young Seok, Shin, Eui‐Cheol, Song, Gi‐Won, Hwang, Shin, Park, Su‐Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154753/
https://www.ncbi.nlm.nih.gov/pubmed/31353502
http://dx.doi.org/10.1002/hep.30881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154753/
https://www.ncbi.nlm.nih.gov/pubmed/31353502
http://dx.doi.org/10.1002/hep.30881

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