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4‐1BB Delineates Distinct Activation Status of Exhausted Tumor‐Infiltrating CD8(+) T Cells in Hepatocellular Carcinoma
BACKGROUND AND AIMS: Targeting costimulatory receptors with agonistic antibodies is a promising cancer immunotherapy option. We aimed to investigate costimulatory receptor expression, particularly 4‐1BB (CD137 or tumor necrosis factor receptor superfamily member 9), on tumor‐infiltrating CD8(+) T ce...
Autores principales: | Kim, Hyung‐Don, Park, Seongyeol, Jeong, Seongju, Lee, Yong Joon, Lee, Hoyoung, Kim, Chang Gon, Kim, Kyung Hwan, Hong, Seung‐Mo, Lee, Jung‐Yun, Kim, Sunghoon, Kim, Hong Kwan, Min, Byung Soh, Chang, Jong Hee, Ju, Young Seok, Shin, Eui‐Cheol, Song, Gi‐Won, Hwang, Shin, Park, Su‐Hyung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154753/ https://www.ncbi.nlm.nih.gov/pubmed/31353502 http://dx.doi.org/10.1002/hep.30881 |
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