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Bioavailability and safety of diazepam intranasal solution compared to oral and rectal diazepam in healthy volunteers
OBJECTIVE: The study assesses the bioavailability of diazepam after intranasal administration (diazepam nasal spray) in healthy volunteers. Comparative agents were diazepam rectal gel, which served as the regulatory reference product; and oral diazepam, a product with decades of clinical use. Tolera...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154760/ https://www.ncbi.nlm.nih.gov/pubmed/32065672 http://dx.doi.org/10.1111/epi.16449 |