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What Does the Molecular Genetics of Different Types of Restorer-of-Fertility Genes Imply?
Cytoplasmic male sterility (CMS) is a widely used trait for hybrid seed production. Although male sterility is caused by S cytoplasm (male-sterility inducing mitochondria), the action of S cytoplasm is suppressed by restorer-of-fertility (Rf), a nuclear gene. Hence, the genetics of Rf has attained p...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154926/ https://www.ncbi.nlm.nih.gov/pubmed/32182978 http://dx.doi.org/10.3390/plants9030361 |
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author | Kubo, Tomohiko Arakawa, Takumi Honma, Yujiro Kitazaki, Kazuyoshi |
author_facet | Kubo, Tomohiko Arakawa, Takumi Honma, Yujiro Kitazaki, Kazuyoshi |
author_sort | Kubo, Tomohiko |
collection | PubMed |
description | Cytoplasmic male sterility (CMS) is a widely used trait for hybrid seed production. Although male sterility is caused by S cytoplasm (male-sterility inducing mitochondria), the action of S cytoplasm is suppressed by restorer-of-fertility (Rf), a nuclear gene. Hence, the genetics of Rf has attained particular interest among plant breeders. The genetic model posits Rf diversity in which an Rf specifically suppresses the cognate S cytoplasm. Molecular analysis of Rf loci in plants has identified various genes; however, pentatricopeptide repeat (PPR) protein (a specific type of RNA-binding protein) is so prominent as the Rf-gene product that Rfs have been categorized into two classes, PPR and non-PPR. In contrast, several shared features between PPR- and some non-PPR Rfs are apparent, suggesting the possibility of another grouping. Our present focus is to group Rfs by molecular genetic classes other than the presence of PPRs. We propose three categories that define partially overlapping groups of Rfs: association with post-transcriptional regulation of mitochondrial gene expression, resistance gene-like copy number variation at the locus, and lack of a direct link to S-orf (a mitochondrial ORF associated with CMS). These groups appear to reflect their own evolutionary background and their mechanism of conferring S cytoplasm specificity. |
format | Online Article Text |
id | pubmed-7154926 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-71549262020-04-21 What Does the Molecular Genetics of Different Types of Restorer-of-Fertility Genes Imply? Kubo, Tomohiko Arakawa, Takumi Honma, Yujiro Kitazaki, Kazuyoshi Plants (Basel) Review Cytoplasmic male sterility (CMS) is a widely used trait for hybrid seed production. Although male sterility is caused by S cytoplasm (male-sterility inducing mitochondria), the action of S cytoplasm is suppressed by restorer-of-fertility (Rf), a nuclear gene. Hence, the genetics of Rf has attained particular interest among plant breeders. The genetic model posits Rf diversity in which an Rf specifically suppresses the cognate S cytoplasm. Molecular analysis of Rf loci in plants has identified various genes; however, pentatricopeptide repeat (PPR) protein (a specific type of RNA-binding protein) is so prominent as the Rf-gene product that Rfs have been categorized into two classes, PPR and non-PPR. In contrast, several shared features between PPR- and some non-PPR Rfs are apparent, suggesting the possibility of another grouping. Our present focus is to group Rfs by molecular genetic classes other than the presence of PPRs. We propose three categories that define partially overlapping groups of Rfs: association with post-transcriptional regulation of mitochondrial gene expression, resistance gene-like copy number variation at the locus, and lack of a direct link to S-orf (a mitochondrial ORF associated with CMS). These groups appear to reflect their own evolutionary background and their mechanism of conferring S cytoplasm specificity. MDPI 2020-03-13 /pmc/articles/PMC7154926/ /pubmed/32182978 http://dx.doi.org/10.3390/plants9030361 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Kubo, Tomohiko Arakawa, Takumi Honma, Yujiro Kitazaki, Kazuyoshi What Does the Molecular Genetics of Different Types of Restorer-of-Fertility Genes Imply? |
title | What Does the Molecular Genetics of Different Types of Restorer-of-Fertility Genes Imply? |
title_full | What Does the Molecular Genetics of Different Types of Restorer-of-Fertility Genes Imply? |
title_fullStr | What Does the Molecular Genetics of Different Types of Restorer-of-Fertility Genes Imply? |
title_full_unstemmed | What Does the Molecular Genetics of Different Types of Restorer-of-Fertility Genes Imply? |
title_short | What Does the Molecular Genetics of Different Types of Restorer-of-Fertility Genes Imply? |
title_sort | what does the molecular genetics of different types of restorer-of-fertility genes imply? |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154926/ https://www.ncbi.nlm.nih.gov/pubmed/32182978 http://dx.doi.org/10.3390/plants9030361 |
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