Cargando…

Automated radiosynthesis of [(11)C]UCB‐J for imaging synaptic density by positron emission tomography

An automated radiosynthesis of carbon‐11 positron emission tomography radiotracer [(11)C]UCB‐J for imaging the synaptic density biomarker synaptic vesicle glycoprotein SV2A was established using Synthra RNPlus synthesizer. Commercially available trifluoroborate UCB‐J analogue was used as a radiolabe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Milicevic Sephton, Selena, Miklovicz, Tunde, Russell, Joseph J., Doke, Aniruddha, Li, Lei, Boros, Istvan, Aigbirhio, Franklin I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Protocols and Methods
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155065/ https://www.ncbi.nlm.nih.gov/pubmed/32027052 http://dx.doi.org/10.1002/jlcr.3828

Ejemplares similares

Synaptic Loss in Frontotemporal Dementia Revealed by [ (11)C]UCB‐J Positron Emission Tomography
por: Malpetti, Maura, et al.
Publicado: (2022)

(11)C-UCB-J synaptic PET and multimodal imaging in dementia with Lewy bodies
por: Nicastro, Nicolas, et al.
Publicado: (2020)

Synaptic density in carriers of C9orf72 mutations: a [(11)C]UCB‐J PET study
por: Malpetti, Maura, et al.
Publicado: (2021)

Measuring brain synaptic vesicle protein 2A with positron emission tomography and [(18)F]UCB-H
por: Bahri, Mohamed Ali, et al.
Publicado: (2017)

Molecular pathology and synaptic loss in primary tauopathies: an (18)F-AV-1451 and (11)C-UCB-J PET study
por: Holland, Negin, et al.
Publicado: (2021)

Radiosynthesis of (R,S)‐[(18)F]GE387: A Potential PET Radiotracer for Imaging Translocator Protein 18 kDa (TSPO) with Low Binding Sensitivity to the Human Gene Polymorphism rs6971
por: Qiao, Luxi, et al.
Publicado: (2019)

Optimized and Automated Radiosynthesis of [(18)F]DHMT for Translational Imaging of Reactive Oxygen Species with Positron Emission Tomography
por: Zhang, Wenjie, et al.
Publicado: (2016)

Identifying brain networks in synaptic density PET ((11)C-UCB-J) with independent component analysis
por: Fang, Xiaotian T., et al.
Publicado: (2021)

Human biodistribution and dosimetry of [(11)C]-UCB-J, a PET radiotracer for imaging synaptic density
por: Cawthorne, Christopher, et al.
Publicado: (2021)

Feasibility of imaging synaptic density in the human spinal cord using [(11)C]UCB-J PET
por: Rossano, Samantha, et al.
Publicado: (2022)

Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [(11)C]UCB‐J
por: Mecca, Adam P., et al.
Publicado: (2022)

Principal component analysis of synaptic density measured with [(11)C]UCB-J PET in early Alzheimer’s disease
por: O'Dell, Ryan S., et al.
Publicado: (2023)

Radiosynthesis of [(18)F]-Labelled Pro-Nucleotides (ProTides)
por: Cavaliere, Alessandra, et al.
Publicado: (2020)

Human adult and adolescent biodistribution and dosimetry of the synaptic vesicle glycoprotein 2A radioligand (11)C-UCB-J
por: Bini, Jason, et al.
Publicado: (2020)

Radiosynthesis, Preclinical, and Clinical Positron Emission Tomography Studies of Carbon-11 Labeled Endogenous and Natural Exogenous Compounds
por: Shegani, Antonio, et al.
Publicado: (2022)

Validation and noninvasive kinetic modeling of [(11)C]UCB-J PET imaging in mice
por: Bertoglio, Daniele, et al.
Publicado: (2019)

Radiosynthesis and Evaluation of [(11)C-Carbonyl]-Labeled Carbamates as Fatty Acid Amide Hydrolase Radiotracers for Positron Emission Tomography
por: Wilson, Alan A., et al.
Publicado: (2012)

Correction to “Radiosynthesis, Preclinical and Clinical Positron Emission Tomography Studies of Carbon-11 Labeled Endogenous and Natural Exogenous Compounds”
por: Shegani, Antonio, et al.
Publicado: (2023)

Potential of [(11)C]UCB-J as a PET tracer for islets of Langerhans
por: Puuvuori, Emmi, et al.
Publicado: (2021)

Automated radiosynthesis of [(68)Ga]Ga‐PSMA‐11 and [(177)Lu]Lu‐PSMA‐617 on the iPHASE MultiSyn module for clinical applications
por: Wichmann, Christian W., et al.
Publicado: (2020)

Association of Aβ deposition and regional synaptic density in early Alzheimer’s disease: a PET imaging study with [(11)C]UCB-J
por: O’Dell, Ryan S., et al.
Publicado: (2021)

Improved synthesis of SV2A targeting radiotracer [(11)C]UCB-J
por: Rokka, Johanna, et al.
Publicado: (2019)

Linking resting-state network fluctuations with systems of coherent synaptic density: A multimodal fMRI and (11)C-UCB-J PET study
por: Fang, Xiaotian T., et al.
Publicado: (2023)

Radiosynthesis and Evaluation of an (18)F-Labeled Positron Emission Tomography (PET) Radioligand for Metabotropic Glutamate Receptor Subtype 4 (mGlu(4))
por: Kil, Kun-Eek, et al.
Publicado: (2014)

Radiosynthesis and Biological Investigation of a Novel Fluorine-18 Labeled Benzoimidazotriazine-Based Radioligand for the Imaging of Phosphodiesterase 2A with Positron Emission Tomography
por: Ritawidya, Rien, et al.
Publicado: (2019)

Partial volume correction analysis for (11)C-UCB-J PET studies of Alzheimer’s disease
por: Lu, Yihuan, et al.
Publicado: (2021)

Validation and test–retest repeatability performance of parametric methods for [(11)C]UCB-J PET
por: Tuncel, Hayel, et al.
Publicado: (2022)

UCB HCT in FLT3+ AML
por: Ustun, Celalettin, et al.
Publicado: (2017)

Improved Automated Radiosynthesis of [(11)C]PBR28
por: Solingapuram Sai, Kiran Kumar, et al.
Publicado: (2015)

Radiosynthesis and Early Evaluation of a Positron Emission Tomography Imaging Probe [(18)F]AGAL Targeting Alpha-Galactosidase A Enzyme for Fabry Disease
por: Lohith, Talakad G., et al.
Publicado: (2023)

Automated One-pot Radiosynthesis of [(11)C]S-adenosyl Methionine
por: Zoppolo, Florencia, et al.
Publicado: (2017)

Pitfalls and solutions of the fully-automated radiosynthesis of [(11)C]metoclopramide
por: Pichler, Verena, et al.
Publicado: (2019)

Fully Automated, High-Dose Radiosynthesis of [(18)F]PARPi
por: Pacelli, Anna, et al.
Publicado: (2022)

Kinetics and 28-day test–retest repeatability and reproducibility of [(11)C]UCB-J PET brain imaging
por: Tuncel, Hayel, et al.
Publicado: (2020)

Vascular Imaging With (18)F-Fluorodeoxyglucose Positron Emission Tomography Is Influenced by Hypoxia
por: Joshi, Francis R., et al.
Publicado: (2017)

Sapap3 deletion causes dynamic synaptic density abnormalities: a longitudinal [(11)C]UCB-J PET study in a model of obsessive–compulsive disorder-like behaviour
por: Glorie, Dorien, et al.
Publicado: (2020)

Standard method for performing positron emission particle tracking (PEPT) measurements of froth flotation at PEPT Cape Town
por: Cole, Katie, et al.
Publicado: (2022)

Robust and Facile Automated Radiosynthesis of [(18)F]FSPG on the GE FASTlab
por: Edwards, Richard, et al.
Publicado: (2021)

A simple and efficient automated microvolume radiosynthesis of [(18)F]Florbetaben
por: Lisova, Ksenia, et al.
Publicado: (2020)

Assessment of synaptic loss in mouse models of β-amyloid and tau pathology using [(18)F]UCB-H PET imaging
por: Vogler, Letizia, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_62dqqd2983cpnq8jhcdo5io8hr