Ca(2+)-based allosteric switches and shape shifting in RGLG1 VWA domain

RGLG1 is an E3 ubiquitin ligase in Arabidopsis thaliana that participates in ABA signaling and regulates apical dominance. Here, we present crystal structures of RGLG1 VWA domain, revealing two novel calcium ions binding sites (NCBS1 and NCBS2). Furthermore, the structures with guided mutagenesis in...

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Detalles Bibliográficos
Autores principales: Wang, Qin, Chen, YaYu, Li, ShengPing, Yang, WenDi, Sun, LiFang, Jang, MeiQin, Wu, XiuLing, Wang, QianChao, Chen, Lifei, Wu, YunKun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155146/
https://www.ncbi.nlm.nih.gov/pubmed/32308929
http://dx.doi.org/10.1016/j.csbj.2020.03.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155146/
https://www.ncbi.nlm.nih.gov/pubmed/32308929
http://dx.doi.org/10.1016/j.csbj.2020.03.023

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