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Synthesis and characterisation of thiobarbituric acid enamine derivatives, and evaluation of their α-glucosidase inhibitory and anti-glycation activity

A new series of thiobarbituric (thiopyrimidine trione) enamine derivatives and its analogues barbituric acid derivatives was synthesised, characterised, and screen for in vitro evaluation of α-glucosidase enzyme inhibition and anti-glycation activity. This series of compounds were found to inhibit α...

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Detalles Bibliográficos
Autores principales: Ali, M., Barakat, Assem, El-Faham, Ayman, Al-Rasheed, Hessa H., Dahlous, Kholoud, Al-Majid, Abdullah Mohammed, Sharma, Anamika, Yousuf, Sammer, Sanam, Mehar, Ul-Haq, Zaheer, Choudhary, M. Iqbal, de la Torre, Beatriz G., Albericio, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155210/
https://www.ncbi.nlm.nih.gov/pubmed/32156165
http://dx.doi.org/10.1080/14756366.2020.1737045

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