NEUROVIRULENCE AND PERSISTENCY OF MOUSE HEPATITIS VIRUSES IN RATS

The murine coronavirus JHM induces in weanling rats different types of central nervous diseases ranging from an acute panencephalitis to a late demyelinating encephalomyelitis. The occurrence and rate of these different disease types is associated with the virus variant used for inoculation. Except...

Descripción completa

Detalles Bibliográficos
Autores principales: Wege, H., Koga, M., Stephenson, J.R., Siddell, S., ter Meulen, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 1980
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155488/
http://dx.doi.org/10.1016/B978-0-12-255850-4.50067-6
_version_ 1783522040702042112
author Wege, H.
Koga, M.
Stephenson, J.R.
Siddell, S.
ter Meulen, V.
author_facet Wege, H.
Koga, M.
Stephenson, J.R.
Siddell, S.
ter Meulen, V.
author_sort Wege, H.
collection PubMed
description The murine coronavirus JHM induces in weanling rats different types of central nervous diseases ranging from an acute panencephalitis to a late demyelinating encephalomyelitis. The occurrence and rate of these different disease types is associated with the virus variant used for inoculation. Except for MHV 2, neurovirulence was not observed in four other murine coronavirus strains. The relationship of these coronaviruses to JHM was investigated by cross neutralization and oligonucleotide maps of their genomic RNA.
format Online
Article
Text
id pubmed-7155488
institution National Center for Biotechnology Information
language English
publishDate 1980
record_format MEDLINE/PubMed
spelling pubmed-71554882020-04-15 NEUROVIRULENCE AND PERSISTENCY OF MOUSE HEPATITIS VIRUSES IN RATS Wege, H. Koga, M. Stephenson, J.R. Siddell, S. ter Meulen, V. Animal Virus Genetics Article The murine coronavirus JHM induces in weanling rats different types of central nervous diseases ranging from an acute panencephalitis to a late demyelinating encephalomyelitis. The occurrence and rate of these different disease types is associated with the virus variant used for inoculation. Except for MHV 2, neurovirulence was not observed in four other murine coronavirus strains. The relationship of these coronaviruses to JHM was investigated by cross neutralization and oligonucleotide maps of their genomic RNA. 1980 2013-11-17 /pmc/articles/PMC7155488/ http://dx.doi.org/10.1016/B978-0-12-255850-4.50067-6 Text en Copyright © 1980 ACADEMIC PRESS, INC. Published by Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Wege, H.
Koga, M.
Stephenson, J.R.
Siddell, S.
ter Meulen, V.
NEUROVIRULENCE AND PERSISTENCY OF MOUSE HEPATITIS VIRUSES IN RATS
title NEUROVIRULENCE AND PERSISTENCY OF MOUSE HEPATITIS VIRUSES IN RATS
title_full NEUROVIRULENCE AND PERSISTENCY OF MOUSE HEPATITIS VIRUSES IN RATS
title_fullStr NEUROVIRULENCE AND PERSISTENCY OF MOUSE HEPATITIS VIRUSES IN RATS
title_full_unstemmed NEUROVIRULENCE AND PERSISTENCY OF MOUSE HEPATITIS VIRUSES IN RATS
title_short NEUROVIRULENCE AND PERSISTENCY OF MOUSE HEPATITIS VIRUSES IN RATS
title_sort neurovirulence and persistency of mouse hepatitis viruses in rats
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155488/
http://dx.doi.org/10.1016/B978-0-12-255850-4.50067-6
work_keys_str_mv AT wegeh neurovirulenceandpersistencyofmousehepatitisvirusesinrats
AT kogam neurovirulenceandpersistencyofmousehepatitisvirusesinrats
AT stephensonjr neurovirulenceandpersistencyofmousehepatitisvirusesinrats
AT siddells neurovirulenceandpersistencyofmousehepatitisvirusesinrats
AT termeulenv neurovirulenceandpersistencyofmousehepatitisvirusesinrats

Ejemplares similares