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Binding of the Human 14-3-3 Isoforms to Distinct Sites in the Leucine-Rich Repeat Kinase 2

Proteins of the 14-3-3 family are well known modulators of the leucine-rich repeat kinase 2 (LRRK2) regulating kinase activity, cellular localization, and ubiquitylation. Although binding between those proteins has been investigated, a comparative study of all human 14-3-3 isoforms interacting with...

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Detalles Bibliográficos
Autores principales: Manschwetus, Jascha T., Wallbott, Maximilian, Fachinger, Alexandra, Obergruber, Claudia, Pautz, Sabine, Bertinetti, Daniela, Schmidt, Sven H., Herberg, Friedrich W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155755/
https://www.ncbi.nlm.nih.gov/pubmed/32317922
http://dx.doi.org/10.3389/fnins.2020.00302

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