Prostate cancer risk prediction models in Eastern Asian populations: current status, racial difference, and future directions

Prostate cancer (PCa) risk calculators (RCs) with prostate-specific antigen (PSA) and other risk factors can greatly improve the accurate prediction of potential risk of PCa compared to PSA. The European Randomized Study of Screening for PCa Risk Calculator (ERSPC-RC) and the Prostate Cancer Prevent...

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Detalles Bibliográficos
Autores principales: He, Bi-Ming, Chen, Rui, Sun, Tian-Qi, Yang, Yue, Zhang, Chun-Lei, Ren, Shan-Cheng, Gao, Xu, Sun, Ying-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155801/
https://www.ncbi.nlm.nih.gov/pubmed/31187780
http://dx.doi.org/10.4103/aja.aja_55_19
Descripción
Sumario:Prostate cancer (PCa) risk calculators (RCs) with prostate-specific antigen (PSA) and other risk factors can greatly improve the accurate prediction of potential risk of PCa compared to PSA. The European Randomized Study of Screening for PCa Risk Calculator (ERSPC-RC) and the Prostate Cancer Prevention Trial Risk Calculator (PCPT-RC) are developed on the Western population. However, the Western RCs showed limited diagnostic efficacy in the Eastern Asian population, mainly due to racial differences between the two populations. We aimed to review the application of Western RCs and Eastern Asian RCs in Eastern Asian cohorts and to identify the characteristics and efficacy of these RCs.

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