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Role of Nucleophosmin Gene Mutation in Leukemogenesis of Acute Myeloid Leukemia

BACKGROUND: Acute myeloid leukemia (AML) is a hematopoietic stem cell disorder that carries very poor prognosis. Understanding molecular basis of AML leukemogenesis could lead to the emergence of effective targeted therapies for AML. AML bearing nucleophosmin (NPM) gene mutation has distinct feature...

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Detalles Bibliográficos
Autores principales: Khaled, Safaa A.A., Burthem, John, Abo Elnoor, El-Badry E., ElToni, Lobna F., Ahmed, Hanan M., Ahmed, Sohier M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155854/
https://www.ncbi.nlm.nih.gov/pubmed/32300405
http://dx.doi.org/10.14740/jh365w

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