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Patch test results in paediatric patients with atopic dermatitis in Laos

BACKGROUND: Dermatological services in Laos, South East Asia are limited mainly to the capital and patch testing is currently not available, so no data exists regarding the common cutaneous allergens in this population. OBJECTIVES: The aim of this study was to document common allergens in paediatric...

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Autores principales: Wootton, Catriona I., Sodaly, Mong K., Billamay, Somxay X., English, John S. C., Mayfong, Mayxay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156065/
https://www.ncbi.nlm.nih.gov/pubmed/32287282
http://dx.doi.org/10.1371/journal.pone.0231455
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author Wootton, Catriona I.
Sodaly, Mong K.
Billamay, Somxay X.
English, John S. C.
Mayfong, Mayxay
author_facet Wootton, Catriona I.
Sodaly, Mong K.
Billamay, Somxay X.
English, John S. C.
Mayfong, Mayxay
author_sort Wootton, Catriona I.
collection PubMed
description BACKGROUND: Dermatological services in Laos, South East Asia are limited mainly to the capital and patch testing is currently not available, so no data exists regarding the common cutaneous allergens in this population. OBJECTIVES: The aim of this study was to document common allergens in paediatric patients with atopic dermatitis attending the allergy clinic in the capital, Vientiane. PATIENTS/MATERIALS/METHODS: Fifty paediatric patients with atopic dermatitis were patch tested using TRUE Test® panels 1 to 3 (35 allergens). Readings were taken at Days 2 and 4. RESULTS: Twenty-six positive patch tests were recorded on Day 4 in 15 children (30%). The most common allergens were: gold (18%), nickel (10%), formaldehyde (6%) and p-Phenylenediamine (6%). Other positive allergens were potassium dichromate (2%), cobalt dichloride (2%), Bronopol (2%), paraben mix (2%), fragrance mix 1 (2%) and neomycin (2%). The majority of the patients with positive reactions were female. CONCLUSIONS: This study represents the first documented patch test results in the Lao population. It is hoped that these findings will help clinicians to advise the families of children with atopic dermatitis on common allergens to avoid and inform future work on contact dermatitis in this population.
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spelling pubmed-71560652020-04-16 Patch test results in paediatric patients with atopic dermatitis in Laos Wootton, Catriona I. Sodaly, Mong K. Billamay, Somxay X. English, John S. C. Mayfong, Mayxay PLoS One Research Article BACKGROUND: Dermatological services in Laos, South East Asia are limited mainly to the capital and patch testing is currently not available, so no data exists regarding the common cutaneous allergens in this population. OBJECTIVES: The aim of this study was to document common allergens in paediatric patients with atopic dermatitis attending the allergy clinic in the capital, Vientiane. PATIENTS/MATERIALS/METHODS: Fifty paediatric patients with atopic dermatitis were patch tested using TRUE Test® panels 1 to 3 (35 allergens). Readings were taken at Days 2 and 4. RESULTS: Twenty-six positive patch tests were recorded on Day 4 in 15 children (30%). The most common allergens were: gold (18%), nickel (10%), formaldehyde (6%) and p-Phenylenediamine (6%). Other positive allergens were potassium dichromate (2%), cobalt dichloride (2%), Bronopol (2%), paraben mix (2%), fragrance mix 1 (2%) and neomycin (2%). The majority of the patients with positive reactions were female. CONCLUSIONS: This study represents the first documented patch test results in the Lao population. It is hoped that these findings will help clinicians to advise the families of children with atopic dermatitis on common allergens to avoid and inform future work on contact dermatitis in this population. Public Library of Science 2020-04-14 /pmc/articles/PMC7156065/ /pubmed/32287282 http://dx.doi.org/10.1371/journal.pone.0231455 Text en © 2020 Wootton et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Wootton, Catriona I.
Sodaly, Mong K.
Billamay, Somxay X.
English, John S. C.
Mayfong, Mayxay
Patch test results in paediatric patients with atopic dermatitis in Laos
title Patch test results in paediatric patients with atopic dermatitis in Laos
title_full Patch test results in paediatric patients with atopic dermatitis in Laos
title_fullStr Patch test results in paediatric patients with atopic dermatitis in Laos
title_full_unstemmed Patch test results in paediatric patients with atopic dermatitis in Laos
title_short Patch test results in paediatric patients with atopic dermatitis in Laos
title_sort patch test results in paediatric patients with atopic dermatitis in laos
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156065/
https://www.ncbi.nlm.nih.gov/pubmed/32287282
http://dx.doi.org/10.1371/journal.pone.0231455
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