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REG-O3 chimeric peptide combining growth hormone and somatostatin sequences improves joint function and prevents cartilage degradation in rat model of traumatic knee osteoarthritis

OBJECTIVE: REG-O3 is a 24-aminoacid chimeric peptide combining a sequence derived from growth hormone (GH) and an analog of somatostatin (SST), molecules displaying cartilage repair and anti-inflammatory properties, respectively. This study aimed to investigate the disease-modifying osteoarthritis d...

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Detalles Bibliográficos
Autores principales:	Montjean, Rodrick, Escaich, Sonia, Paolini, Raffaello, Carelli, Claude, Pirson, Sébastien, Neutelings, Thibaut, Henrotin, Yves, Vêtu, Christelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156079/ https://www.ncbi.nlm.nih.gov/pubmed/32287299 http://dx.doi.org/10.1371/journal.pone.0231240

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