Establishment of an induced pluripotent stem cell line (FDEENTi002-A) from a patient with Best’s disease carrying c.888C > A mutation in BEST1 gene

Best’s disease (BD) is an inherited retinal degenerative disease caused by mutations in BEST1 gene. A human induced pluripotent stem cell (iPSC) line has been generated with integration-free Sendai virus method from peripheral blood mononuclear cells (PBMCs) of a BD patient carrying c.888C > A mu...

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Detalles Bibliográficos
Autores principales: Bai, Xinyue, Yang, Xian-Jie, Chen, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156156/
https://www.ncbi.nlm.nih.gov/pubmed/31146250
http://dx.doi.org/10.1016/j.scr.2019.101459
Descripción
Sumario:Best’s disease (BD) is an inherited retinal degenerative disease caused by mutations in BEST1 gene. A human induced pluripotent stem cell (iPSC) line has been generated with integration-free Sendai virus method from peripheral blood mononuclear cells (PBMCs) of a BD patient carrying c.888C > A mutation in BEST1 gene. This cell line may serve as a model for the study of pathogenesis of BD.

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