CSF1R blockade induces macrophage ablation and results in mouse choroidal vascular atrophy and RPE disorganization

The choroid, which provides vascular supply to the outer retina, demonstrates progressive degeneration in aging and age-related macular degeneration (AMD). However mechanisms that maintain or compromise choroidal homeostasis are obscure. We discovered that the ablation of choroidal macrophages via C...

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Detalles Bibliográficos
Autores principales: Yang, Xiao, Zhao, Lian, Campos, Maria M, Abu-Asab, Mones, Ortolan, Davide, Hotaling, Nathan, Bharti, Kapil, Wong, Wai T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156269/
https://www.ncbi.nlm.nih.gov/pubmed/32234210
http://dx.doi.org/10.7554/eLife.55564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156269/
https://www.ncbi.nlm.nih.gov/pubmed/32234210
http://dx.doi.org/10.7554/eLife.55564

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