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Dynamic changes in the regulatory T-cell heterogeneity and function by murine IL-2 mutein

The therapeutic expansion of Foxp3(+) regulatory T cells (Tregs) shows promise for treating autoimmune and inflammatory disorders. Yet, how this treatment affects the heterogeneity and function of Tregs is not clear. Using single-cell RNA-seq analysis, we characterized 31,908 Tregs from the mice tre...

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Detalles Bibliográficos
Autores principales:	Lu, Daniel R, Wu, Hao, Driver, Ian, Ingersoll, Sarah, Sohn, Sue, Wang, Songli, Li, Chi-Ming, Phee, Hyewon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156283/ https://www.ncbi.nlm.nih.gov/pubmed/32269069 http://dx.doi.org/10.26508/lsa.201900520

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